{"product_id":"jonexa-up-siringa-intra-articolare-sodio-ialuronato-cross-linkato-2-4-4-ml","title":"JONEXA UP INTRA-ARTICULAR SYRINGE CROSS-LINKED SODIUM HYALURONATE 2% 4.4 ML","description":"\u003ch1\u003eJonexa UP\u003c\/h1\u003e \u003cdiv align=\"justify\"\u003e \u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Biocompatible hydrogel of cross-linked sodium hyaluronate obtained through bio-fermentation and highly purified, dissolved in a physiological and isotonic buffer. The product is an injectable, sterile and pyrogen-free hydrogel, with a low endotoxin level.\u003cbr\u003e JONEXA UP is formulated with highly purified sodium hyaluronate, salts of quality compliant with Pharmacopoeia requirements, and water for injections.\u003cbr\u003e JONEXA UP reduces pain and increases the functionality of the affected joint.\u003cbr\u003e JONEXA UP provides a lubricating and shock-absorbing effect on the affected joint.\u003cbr\u003e JONEXA UP improves the patient's quality of life.\u003cbr\u003e JONEXA UP must be administered by intra-articular injection by a qualified physician following all rules regarding aseptic procedure and injection technique.\u003cbr\u003e JONEXA UP should be injected with a suitable sterile needle (18-21G needles are recommended).\u003cbr\u003e It is recommended to administer JONEXA UP in a single session. The amount of product to be administered is at the discretion of the specialist physician. Discard any unused part of the syringe.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eHow to use\u003c\/b\u003e\u003cbr\u003e JONEXA UP should be injected into the joint in the synovial space of the knee, as a viscosupplementation for the synovial fluid, when the fluid's viscosity is reduced due to the osteoarthritis process, in patients who have not responded adequately to non-pharmacological conservative therapy and simple analgesics.\u003cbr\u003e 1. Before injection, the area to be treated must be thoroughly disinfected, and the product brought to room temperature.\u003cbr\u003e 2. Open the sterile packaging and remove the syringe from inside.\u003cbr\u003e 3. Remove the syringe cap without touching it, to keep it sterile.\u003cbr\u003e 4. Connect a suitable sterile needle (18-21G needles are recommended) to the syringe tip.\u003cbr\u003e Ensure the needle is correctly locked onto the syringe's Luer-lock adapter before use.\u003cbr\u003e 5. Remove air from the syringe, if necessary.\u003cbr\u003e 6. Inject into the joint in the synovial space of the affected knee, following aseptic injection procedures.\u003cbr\u003e 7. At the end of the treatment session, discard the syringe and any remaining product.\u003cbr\u003e The amount of product to be administered is at the discretion of the specialist physician; the recommended dose is 3-4 ml for each knee joint.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Cross-linked sodium hyaluronate 20 mg\/ml, disodium phosphate dodecahydrate 0.6 mg\/ml, sodium dihydrogen phosphate dihydrate 0.05 mg\/ml, sodium chloride 8 mg\/ml, water for injections q.s.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eWarnings\u003c\/b\u003e\u003cbr\u003e Do not administer JONEXA UP to patients with known hypersensitivity (allergy) to hyaluronic acid and\/or other components of the product.\u003cbr\u003e Do not administer JONEXA UP to patients with acute or chronic dermatological disorders or with inflammatory and\/or infectious skin problems.\u003cbr\u003e Do not administer JONEXA UP to patients with coagulation disorders and\/or undergoing treatment with anticoagulant drugs.\u003cbr\u003e JONEXA UP should not be administered to pregnant or breastfeeding women.\u003cbr\u003e JONEXA UP should not be administered to children.\u003cbr\u003e The use of JONEXA UP in any joint other than the knee and for other conditions has not been studied.\u003cbr\u003e JONEXA UP must be strictly injected into the intra-articular space following aseptic injection procedures.\u003cbr\u003e JONEXA UP must be administered with sterile Luer-lock needles.\u003cbr\u003e Do not inject into a blood vessel or surrounding tissues. To avoid pain after injection, it is recommended to keep the local injection site still.\u003cbr\u003e The product must not be used if the packaging is damaged or broken.\u003cbr\u003e The product must not be used after the expiration date.\u003cbr\u003e The product is for single-use only. Do not reuse; risk of infection.\u003cbr\u003e Do not re-sterilize; re-sterilization may affect the physical-chemical properties of the product and compromise its efficacy and safety.\u003cbr\u003e The syringe and used needle must be disposed of in a proper container.\u003cbr\u003e Keep out of reach of children.\u003cbr\u003e Do not use with other products containing quaternary ammonium salts such as benzalkonium chloride or with any surgical material treated with this type of substance, as sodium hyaluronate may precipitate in their presence. To prevent any possible interaction, avoid concomitant administration with other intra-articular products.\u003cbr\u003e No interactions with other local anesthetics are known.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eStorage\u003c\/b\u003e\u003cbr\u003e Store between 5 °C and 25 °C. Protect from light and avoid freezing.\u003cbr\u003e Do not use after the date indicated on the packaging.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 4.4 ml syringe.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eCod.\u003c\/b\u003e 6801\u003c\/div\u003e","brand":"ABIOGEN PHARMA SpA","offers":[{"title":"Default Title","offer_id":45944992366859,"sku":"989021011","price":176.63,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/4683\/0859\/files\/GetDoc_ef7c18c9-9f67-4be7-aba7-a685b9812724.jpg?v=1727818697","url":"https:\/\/farmaonline24.it\/en\/products\/jonexa-up-siringa-intra-articolare-sodio-ialuronato-cross-linkato-2-4-4-ml","provider":"FarmaOnline24","version":"1.0","type":"link"}