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GLYCEROL Zeta early childhood 2.25 g rectal solution
GLYCEROL Zeta children 4.5 g rectal solution
GLYCEROL Zeta adults 6.75 g rectal solution
Glycerol
What it is and what it is used for
GLYCEROL Zeta contains the active ingredient glycerol, which belongs to the category of laxatives, medicines used to facilitate bowel movements. This medicine is indicated for the short-term treatment of occasional constipation.
Contact your doctor if you do not notice any improvement or if your symptoms worsen after 7 days.
What you need to know before taking the medicine
Do not use GLYCEROL Zeta
- if you are allergic to glycerol or any of the other ingredients of this medicine (listed in section 6);
- if you suffer from acute or unknown abdominal pain;
- if you have nausea or vomiting;
- if you suffer from intestinal obstruction or narrowing (stenosis);
- if you suffer from unexplained rectal bleeding;
- if you suffer from swollen blood vessels around the anus (acute hemorrhoidal crisis) with pain and bleeding;
- if you are severely dehydrated.
Warnings and precautions
Talk to your doctor or pharmacist before taking GLYCEROL Zeta.
If you are elderly and/or not in good health, inform your doctor before using this medicine.
Use medicines that stimulate bowel movements (laxatives) as infrequently as possible and in any case for no more than 7 days. The use of laxatives for longer periods requires a doctor's prescription, after adequate evaluation of the patient's condition.
If you suffer from constipation that lasts for long periods (chronic) or is frequent, always seek medical intervention for diagnosis, prescription of medicines, and monitoring during therapy. Consult your doctor when the need for a laxative results from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) that has lasted for more than two weeks or when the use of a laxative fails to produce effects.
Drink at least 6-8 glasses of water or other liquids daily to help soften stools when using laxatives.
If you use laxatives excessively, frequently, or incorrectly, you could experience prolonged diarrhea with consequent loss of water, mineral salts (especially potassium), and other essential nutrients. In the most severe cases of abuse, excessive fluid loss (dehydration) or a drop in blood potassium levels (hypokalemia) can occur, which can cause heart or muscle problems, especially if you are taking cardiac glycosides, diuretics, or corticosteroids during treatment with this medicine.
The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause dependence (the need to constantly increase the dosage), chronic constipation, and loss of normal bowel function (intestinal atony).
In case of constipation, first correct your eating habits by consuming an adequate amount of fiber and water in your daily diet.
In most cases, a balanced diet rich in water and fiber (bran, vegetables, and fruit) can permanently solve the problem of constipation. Many people think they suffer from constipation if they do not have a bowel movement every day. This is an incorrect belief as this situation is completely normal for a large number of individuals. True constipation occurs when bowel movements are fewer than usual and are associated with hard stools. If episodes of constipation occur repeatedly, a doctor must be consulted.
Children
For children under 12 years of age, use GLYCEROL Zeta only after consulting a doctor.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects may occur:
Not known (frequency cannot be estimated from the available data)
- Isolated cramp-like pains or abdominal colic and diarrhea, with loss of fluids and mineral salts (electrolytes) more frequent in cases of severe constipation
- Rectal irritation
Reporting of side effects
If you get any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects, you can help provide more information on the safety of this medicine.

