LASONIL PAIN RELIEF*GEL 50G 10%

Lasonil antidolore 10% gel
Ibuprofen lysine salt

What it is and what it is used for
This medicine contains Ibuprofen lysine salt, which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs), which act to relieve pain and reduce symptoms associated with inflammation.

Lasonil antidolore is used for the local treatment of bruises, sprains, myalgia (muscle pain), muscle strains, and torticollis.

Consult your doctor if you do not feel better or if your symptoms worsen.

What you need to know before taking the medicine
Do not use Lasonil antidolore
- if you are allergic to ibuprofen or any of the other ingredients of this medicine (listed in section 6).
- if you are allergic to other analgesics (painkillers), antipyretics (fever reducers), non-steroidal anti-inflammatory drugs (NSAIDs) that have previously caused asthma, rhinitis, urticaria or other allergic manifestations.
- if you are in the last 3 months of pregnancy (see Pregnancy, breastfeeding and fertility).
- if you are breastfeeding (see Pregnancy, breastfeeding and fertility).
- if you are under 14 years of age (see Children and adolescents).
- if you are using other NSAIDs (see Other medicines and Lasonil antidolore).

Warnings and precautions
Consult your doctor or pharmacist before using Lasonil antidolore:
- if you suffer or have ever suffered from asthma, allergic rhinitis, urticaria or other allergic manifestations after using acetylsalicylic acid or other similar anti-inflammatory drugs.
- if you are simultaneously using anticoagulant medicines (drugs used to thin the blood) such as warfarin (see Other medicines and Lasonil antidolore)

It is advisable to avoid applying Lasonil antidolore to open wounds or skin lesions.

Skin reactions

The use of Lasonil antidolore, especially if prolonged, may lead to local sensitization phenomena: at the first appearance of skin rash, mucosal lesions or any other sign of hypersensitivity, discontinue treatment and consult your doctor, who may adopt appropriate therapeutic measures.

To avoid more severe hypersensitivity or photosensitization phenomena (skin erythema after applying the product and subsequent exposure to light, solar or UV), do not expose yourself to direct sunlight, including solarium, during treatment and for two weeks thereafter (see section 4. Possible side effects.).

Severe skin reactions, including exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP) have been reported in association with Lasonil antidolore treatment. Stop using Lasonil antidolore and contact your doctor immediately if you notice any of the symptoms related to these severe skin reactions described in section 4.

Children and adolescents
The use of the medicine is reserved for patients over 14 years of age only.

Possible side effects
Stop using Lasonil Antidolore and consult your doctor immediately if you notice any of the following symptoms:

- non-raised, target-shaped or circular reddish patches on the trunk, often with central blisters, skin peeling, ulcers in the mouth, throat, nose, genitals, and eyes. These severe skin rashes may be preceded by fever and flu-like symptoms [exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis].
- widespread rash, high body temperature, and swollen lymph nodes (DRESS syndrome).
- widespread, red, and scaly rash, with bumps under the skin and blisters, accompanied by fever. Symptoms usually appear at the beginning of treatment (acute generalized exanthematous pustulosis).

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Side effects can be minimized by using the lowest effective dose for the shortest possible duration of treatment needed to control symptoms.

Skin reactions with erythema, itching, irritation, a feeling of warmth or burning, and contact dermatitis have been reported with some non-steroidal anti-inflammatory drugs for skin application.

The skin becomes sensitive to light. Photosensitivity reactions (skin erythema after product application and subsequent exposure to light, solar or UV) are possible, side effects reported with an unknown frequency (i.e., the frequency cannot be estimated from the available data). See also section 2.

Adherence to the instructions in the package leaflet reduces the risk of side effects.

Reporting of side effects
If you get any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects you can help provide more information on the safety of this medicine.