NEOBORO GOLADO*16PST LI&MI S/Z

NEO BOROCILLINA GOLA DOLORE 8.75 mg sugar-free mint flavour lozenges
NEO BOROCILLINA GOLA DOLORE 8.75 mg sugar-free orange and honey flavour lozenges
NEO BOROCILLINA GOLA DOLORE 8.75 mg sugar-free lemon and honey flavour lozenges
flurbiprofen

What it is and what it is used for
Neo Borocillina Gola Dolore contains flurbiprofen. Flurbiprofen belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). These medicines relieve symptoms by changing the body's response to pain and fever.

Neo Borocillina Gola Dolore sugar-free lozenges are used to relieve the symptoms of irritation and inflammation, also associated with pain, of the oropharyngeal cavity (e.g. sore throat, gingivitis and stomatitis).

What you need to know before taking the medicine
DO NOT use Neo Borocillina Gola Dolore lozenges
• if you are allergic to flurbiprofen or any of the other ingredients of this medicine (listed in paragraph 6)
• if you are allergic to acetylsalicylic acid (e.g. aspirin) or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
• if you have high respiratory sensitivity (asthma, bronchospasm)
• if you are allergic and suffer from itching (urticaria)
• if you suffer from stomach lining lesions (peptic ulcer) or have suffered from this disease in the past
• during the third trimester of pregnancy and if you are breastfeeding (see paragraph Pregnancy and breastfeeding)
• in children and adolescents under 12 years of age

Warnings and precautions
Swallowing the lozenges, at the recommended doses, does not cause any harm to the patient, as these doses are much lower than those commonly used in treatments with systemic flurbiprofen.

It is advisable not to use Neo Borocillina Gola Dolore lozenges with other medicines belonging to the category of non-steroidal anti-inflammatory drugs (NSAIDs).

The prolonged use of products for local use may cause allergic reactions. In this case, stop the treatment and consult your doctor.

Consult your doctor or pharmacist if:
- you have an infection - refer to the Infections paragraph below.

Infections
Non-steroidal anti-inflammatory drugs (NSAIDs) can mask signs of infection such as fever and pain. This can delay appropriate treatment of the infection, which, in turn, can lead to an increased risk of complications.

If you are taking this medicine during an infection and the symptoms of the infection persist or worsen, contact your doctor or pharmacist immediately.

Use Neo Borocillina Gola Dolore lozenges with caution:
• if you suffer from reduced kidney function (renal insufficiency) or reduced heart function (heart failure) or reduced liver function (hepatic insufficiency)

Remember:
• that this medicine should not be used for long-term treatments
• to consult your doctor after a short period of treatment if you do not notice any improvement

Children and adolescents
Do not use Neo Borocillina Gola Dolore lozenges in children and adolescents under 12 years of age.

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

The prolonged use of Neo Borocillina Gola Dolore can cause allergic reactions or local irritation. In this case, stop the treatment and consult your doctor for a more appropriate therapy.

Blood problems
• Altered values of some blood tests (thrombocytopenia, aplastic anaemia, agranulocytosis)

Immune system problems
• Allergic reactions, including severe ones (anaphylaxis, swelling of the face, lips and/or tongue)

Nervous system problems
• Dizziness
• Brain damage (stroke)
• Visual disturbances
• Inflammation of the optic nerve (optic neuritis)
• Headache (migraine)
• Sensory disturbances of the limbs and other body parts (paraesthesia)
• Depression
• Confusion
• Hallucination
• Vertigo
• Feeling of discomfort
• Fatigue and drowsiness

Ear problems
• Ringing in the ears (tinnitus)

Respiratory problems
• Narrowing of the airways (bronchospasm)
• Inflammation of the airways (asthma)
• Laboured breathing (dyspnoea)

Gastrointestinal problems
Most commonly observed:
• Nausea
• Vomiting
• Diarrhoea
• Gas production (flatulence)
• Lack of bowel movements (constipation)
• Digestive difficulties (dyspepsia)
• Stomach or abdominal pain
• Blood in the stools (black stools)
• Blood in the vomit (haematemesis)
• Presence of ulcers in the mouth (ulcerative stomatitis)
• Internal bleeding of the digestive system (gastrointestinal haemorrhage)
• Worsening of inflammatory bowel diseases (colitis, Crohn's disease)

Less frequently observed:
• Stomach inflammation (gastritis)
• Internal stomach lesions (peptic ulcer)
• Perforation and bleeding (from ulcer)

Skin problems
• Rashes
• Itching
• Urticaria
• Dark red spots of various sizes (purpura)
• Very rarely severe skin diseases such as Stevens-Johnson syndrome (skin rash and blisters, mouth and eye ulcers), Lyell's syndrome (peeling, painful, red skin) and erythema multiforme (skin lesions)

Kidney and urinary tract problems
• Kidney problems in various forms, including kidney inflammation (interstitial nephritis)
• Alteration of kidney function (nephrotic syndrome)
As with other NSAIDs, rare cases of reduced kidney function (renal insufficiency) have been reported.

Reporting of side effects
If you get any side effects, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects you can help provide more information on the safety of this medicine.