NEOBORO ICE*32 PASTILLES MINT S/F

NEO BOROCILLINA GOLA DOLORE 8.75 mg sugar-free lozenges, mint flavour
NEO BOROCILLINA GOLA DOLORE 8.75 mg sugar-free lozenges, orange and honey flavour
NEO BOROCILLINA GOLA DOLORE 8.75 mg sugar-free lozenges, lemon and honey flavour
flurbiprofen

What it is and what it is used for
Neo Borocillina Gola Dolore contains flurbiprofen. Flurbiprofen belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). These medicines relieve symptoms by modifying the body's response to pain and fever.

Neo Borocillina Gola Dolore sugar-free lozenges are used to relieve symptoms of irritation and inflammation, also associated with pain, of the oropharyngeal cavity (e.g. sore throat, gingivitis and stomatitis).

What you need to know before taking the medicine
DO NOT use Neo Borocillina Gola Dolore lozenges
• if you are allergic to flurbiprofen or any of the other ingredients of this medicine (listed in paragraph 6)
• if you are allergic to acetylsalicylic acid (e.g. aspirin) or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
• if you have high respiratory sensitivity (asthma, bronchospasm)
• if you are an allergic subject and suffer from itching (urticaria)
• if you suffer from gastric mucosal lesions (peptic ulcer) or if you have suffered from this disease in the past
• during the third trimester of pregnancy and if you are breastfeeding (see paragraph Pregnancy and breastfeeding)
• in children and adolescents under 12 years of age

Warnings and precautions
Accidental swallowing of the lozenges, at the recommended doses, does not cause any harm to the patient, as these doses are much lower than those commonly used in systemic flurbiprofen treatments.

It is advisable not to use Neo Borocillina Gola Dolore lozenges with other medicines belonging to the category of non-steroidal anti-inflammatory drugs (NSAIDs).

The use of topical products, especially if prolonged, can cause allergic reactions. In such cases, discontinue treatment and consult your doctor.

Talk to your doctor or pharmacist if:
- you have an infection - refer to the Infections section below.

Infections
Non-steroidal anti-inflammatory drugs (NSAIDs) can mask signs of infection such as fever and pain. This can delay appropriate treatment of the infection, which, in turn, can lead to an increased risk of complications.

If you take this medicine during an infection and the symptoms of the infection persist or worsen, contact your doctor or pharmacist immediately.

Use Neo Borocillina Gola Dolore lozenges with caution:
• if you suffer from reduced kidney function (kidney failure) or reduced heart function (heart failure) or reduced liver function (liver failure)

Remember:
• that this medicine should not be used for long-term treatments
• to consult your doctor after a short period of treatment if you do not notice improvements

Children and adolescents
Do not use Neo Borocillina Gola Dolore lozenges in children and adolescents under 12 years of age.

Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.

The prolonged use of Neo Borocillina Gola Dolore can cause allergic reactions or local irritation. In such cases, discontinue treatment and consult your doctor for a more appropriate therapy.

Blood problems
• Altered values of some blood tests (thrombocytopenia, aplastic anaemia, agranulocytosis)

Immune system problems
• Allergic reactions, including severe ones (anaphylaxis, swelling of the face, lips and/or tongue)

Nervous system problems
• Dizziness
• Brain damage (stroke)
• Visual disturbances
• Inflammation of the optic nerve (optic neuritis)
• Headache (migraine)
• Disturbances of sensitivity of the limbs and other parts of the body (paresthesia)
• Depression
• Confusion
• Hallucination
• Vertigo
• Sense of discomfort
• Fatigue and drowsiness

Ear problems
• Ringing in the ears (tinnitus)

Respiratory problems
• Narrowing of the airways (bronchospasm)
• Inflammation of the airways (asthma)
• Laboured breathing (dyspnoea)

Gastrointestinal problems
Most commonly observed:
• Nausea
• Vomiting
• Diarrhoea
• Gas production (flatulence)
• Lack of bowel movements (constipation)
• Digestive difficulties (dyspepsia)
• Abdominal or stomach pain
• Presence of blood in stools (black stools)
• Presence of blood in vomit (haematemesis)
• Presence of mouth ulcerations (ulcerative stomatitis)
• Internal bleeding of the digestive system (gastrointestinal haemorrhage)
• Worsening of inflammatory bowel diseases (colitis, Crohn's disease)

Less commonly observed:
• Stomach inflammation (gastritis)
• Internal stomach lesions (peptic ulcer)
• Perforation and bleeding (from ulcer)

Skin problems
• Rashes
• Itching
• Urticaria
• Dark red spots of varying size (purpura)
• Very rarely severe skin diseases such as Stevens-Johnson syndrome (rash and blisters, mouth and eye ulcers), Lyell's syndrome (peeling, painful, red skin) and erythema multiforme (skin lesions)

Kidney and urinary tract problems
• Kidney problems in various forms, including kidney inflammation (interstitial nephritis)
• Altered kidney function (nephrotic syndrome)
As with other NSAIDs, rare cases of reduced kidney function (kidney failure) have been reported.

Reporting of side effects
If you get any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects, you can help provide more information on the safety of this medicine.