NEOBORO GOLADO*MINT SPRAY 15ML

NEO BOROCILLINA GOLA DOLORE 0.25% oral spray mint flavor NEO BOROCILLINA GOLA DOLORE 0.25% oral spray orange and honey flavor NEO BOROCILLINA GOLA DOLORE 0.25% oral spray lemon and honey flavor
flurbiprofen

What it is and what it is used for
Neo Borocillina Gola Dolore contains flurbiprofen. Flurbiprofen belongs to a group of medicines called Non-Steroidal Anti-inflammatory Drugs (NSAIDs). These medicines relieve symptoms by changing the body's response to pain and fever.

Neo Borocillina Gola Dolore oral spray is used to relieve the symptoms of irritation and inflammation, also associated with pain, of the oropharyngeal cavity (e.g., sore throat, gingivitis, and stomatitis), even as a result of conservative or extractive dental treatment (dental care and extractions).

What you need to know before taking the medicine
DO NOT use Neo Borocillina Gola Dolore oral spray
• if you are allergic to flurbiprofen or any of the other ingredients of this medicine (listed in paragraph 6)
• if you are allergic to acetylsalicylic acid (e.g., aspirin) or other Non-Steroidal Anti-inflammatory Drugs (NSAIDs)
• if you have high sensitivity of the respiratory system (asthma, bronchospasm)
• if you are allergic and suffer from itching (urticaria)
• if you suffer from stomach lining lesions (peptic ulcer) or if you have suffered from this condition in the past
• during the third trimester of pregnancy and if you are breastfeeding (see paragraph Pregnancy and breastfeeding)

Warnings and precautions
Accidental swallowing of the solution, at the recommended doses, does not cause any harm to the patient, as these doses are much lower than those commonly used in systemic flurbiprofen treatments.

It is recommended not to use Neo Borocillina Gola Dolore oral spray with other medicines belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs).

The prolonged use of products for local application may give rise to allergic reactions. In this case, discontinue treatment and consult your doctor.

Consult your doctor or pharmacist if:
- you have an infection - refer to the Infections paragraph below.

Infections
Non-steroidal anti-inflammatory drugs (NSAIDs) can mask signs of infections such as fever and pain. This can delay appropriate treatment of the infection, which, in turn, can lead to an increased risk of complications.
If you take this medicine during an infection and infection symptoms persist or worsen, contact your doctor or pharmacist immediately.

Use Neo Borocillina Gola Dolore oral spray with caution:
• if you suffer from reduced kidney function (renal insufficiency) or reduced heart function (cardiac insufficiency) or reduced liver function (hepatic insufficiency)

Remember:
• that this medicine should not be used for long-term treatments
• to consult your doctor after a short period of treatment if you do not notice improvements

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

Prolonged use of Neo Borocillina Gola Dolore can cause allergic reactions or local irritation. In such a case, stop the treatment and consult your doctor to get a more appropriate therapy.

Blood problems
• Altered values of some blood tests (thrombocytopenia, aplastic anemia, agranulocytosis)

Immune system problems
• Allergic reactions, including severe ones (anaphylaxis, swelling of the face, lips and/or tongue)

Nervous system problems
• Dizziness
• Brain damage (stroke)
• Visual disturbances
• Inflammation of the optic nerve (optic neuritis)
• Headache (migraine)
• Disturbances of sensation in the limbs and other body parts (paresthesia)
• Depression
• Confusion
• Hallucination
• Vertigo
• Feeling of discomfort
• Fatigue and drowsiness

Ear problems
• Ringing in the ears (tinnitus)

Respiratory problems
• Narrowing of the airways (bronchospasm)
• Inflammation of the airways (asthma)
• Difficulty breathing (dyspnea)

Gastrointestinal problems
Most commonly observed were:
• Nausea
• Vomiting
• Diarrhea
• Gas production (flatulence)
• Lack of bowel movements (constipation)
• Digestive difficulties (dyspepsia)
• Abdominal pain or stomach pain (abdominal pain)
• Blood in stools (black stools)
• Blood in vomit (hematemesis)
• Presence of mouth ulcers (ulcerative stomatitis)
• Internal bleeding of the digestive system (gastrointestinal hemorrhage)
• Worsening of inflammatory bowel diseases (colitis, Crohn's disease)

Less frequently observed were:
• Stomach inflammation (gastritis)
• Internal stomach lesions (peptic ulcer)
• Perforation and bleeding (from ulcer)

Skin problems
• Rashes
• Itching
• Urticaria
• Dark red spots of various sizes (purpura)
• Very rarely severe skin diseases such as Stevens-Johnson syndrome (skin rash and blisters, mouth and eye ulcers), Lyell's syndrome (peeling, painful, red skin) and erythema multiforme (skin lesions)

Kidney and urinary tract problems
• Kidney problems in various forms, including kidney inflammation (interstitial nephritis)
• Alteration of kidney function (nephrotic syndrome)
As with other NSAIDs, rare cases of reduced kidney function (renal insufficiency) have been reported

Reporting side effects
If you get any side effects, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects you can help provide more information on the safety of this medicine.