NORUXOL*OINT 30G

NORUXOL Ointment
Clostridiopeptidase A 1.2 units and protease 0.24 units

What it is and what it is used for
Noruxol ointment contains collagenase N, consisting of Clostridiopeptidase A (collagenase enzyme) and associated proteases. These enzymes are used for wound treatment because they can remove (debride) dry and moist scabs or eschars (necrotic, fibrinous tissue) normally present on wounds, leg ulcers, pressure ulcers, diabetic ulcers, and burns.
By removing scabs and eschars, Noruxol accelerates scar formation and the healing process.
Consult your doctor if you do not feel better or if you feel worse after 14 days.

What you need to know before taking the medicine
Do not use Noruxol
• if you are allergic to clostridiopeptidase, proteases, proteolytic enzymes or any of the other components of this medicine (listed in section 6)

Warnings and precautions
Consult your doctor or pharmacist before using Noruxol if:
• you have been told there is an infection in the wound
• you are diabetic and have been told you have a wound or dry gangrene; in this case, moisten the wound before applying Noruxol, being careful not to make it excessively wet
• you have a severe burn; in this case, you must use Noruxol under the guidance and supervision of a specialist doctor.

The use, especially prolonged use, of topical products (on the skin) can cause sensitization; in this case, stop treatment and consult your doctor or pharmacist.

Avoid contact with eyes and mucous membranes. Do not ingest.

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

With the use of Noruxol, you may experience the following side effects:
• local pain on the wound
• local skin reactions such as itching, burning, erythema

If the reactions are severe, discontinuation of therapy should be considered.

Reporting side effects
If you get any side effects, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects, you can help provide more information on the safety of this medicine.