CONNETTIVINA PLUS*10GAUZES10x10

Connettivina Plus 2 mg + 40 mg impregnated gauzes
Connettivina Plus 4 mg + 80 mg impregnated gauzes
Connettivina Plus 12 mg + 240 mg impregnated gauzes
Hyaluronic acid sodium salt + silver sulfadiazine

What it is and what it is used for
Connettivina Plus impregnated gauzes contain two active ingredients: hyaluronic acid sodium salt and silver sulfadiazine, and belong to a class of medicines called healing and disinfectant agents.

Hyaluronic acid is a substance naturally produced by our body. The local supply of hyaluronic acid facilitates the healing process of lesions.
Silver sulfadiazine is an active ingredient belonging to the family of sulfonamide antibiotics; it is able to block bacterial replication mechanisms and thus counteract the formation of infections.

Connettivina Plus impregnated gauzes are indicated for the local treatment of early-stage sores (before the skin breaks) and for the treatment of minor burns (first and second-degree burns).

What you need to know before taking the medicine
Do not use Connettivina Plus:
if you are allergic to the active ingredient or to any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions
Consult your doctor or pharmacist before using Connettivina Plus if:
- you have had a hypersensitivity reaction (allergic reaction) after taking sulfonamides;
- you have severe liver problems (liver failure);
- you have severe kidney problems (kidney failure);
- you are pregnant or breastfeeding.

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

After applying CONNETTIVINA PLUS gauzes, local reactions (pain, burning, itching), including allergic reactions, may occur.

Following the application of Connettivina Plus to large areas of the skin, you may experience side effects usually observed with the intake of sulfonamide-based medicines (a class of drugs to which sulfadiazine belongs) orally or by injection (systemic routes) such as:
- severe kidney problems (renal failure);
- liver inflammation as a reaction to certain substances to which you are exposed (toxic hepatitis);
- reduction in the number of white blood cells (agranulocytosis and leukopenia) and platelets (thrombocytopenia) circulating in the blood.

Reporting of side effects
If you get any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects you can help provide more information on the safety of this medicine.