Description
Sterile, pyrogen-free, viscoelastic solution produced with sodium hyaluronate, obtained by bacterial fermentation from a high molecular weight fraction (<2.00 kDa). Hyaluronic acid is naturally present in many human tissues such as cartilage and synovial fluid: it is continuously secreted into the joint cavity and represents the major component of synovial fluid to which it provides its characteristic viscosity and elasticity. These properties are fundamental for the fluid to perform its functions as a lubricant and shock absorber in normal joints, in order to protect cartilage and soft tissues from mechanical damage.
Temporary substitute for synovial fluid indicated in the treatment of pain and reduced mobility in patients suffering from degenerative or traumatic arthropathy in the synovial joints. The product acts by providing lubrication and mechanical support and is particularly suitable for the treatment of OA symptoms.

Instructions for use
Using a suitable sterile needle (e.g., 18 or 20 G), into the affected joint at weekly intervals for a total of 3 weeks. If necessary, further injections can be performed. The administration of the product should be performed exclusively by specialist doctors. All rules regarding asepsis and infectious techniques must be observed. If an effusion is present, remove it before injecting the product.

Components
Sodium hyaluronate 1.5%; other components: sodium chloride, dibasic sodium phosphate 2H2O, water for injections.

Warnings
Do not use if the package is damaged. Keep out of reach and sight of children. The content of the pre-filled syringe is sterile. The external surface of the syringe is not sterile, but has a reduced bacterial load. It has not been tested in pregnant women. Do not use the product after the expiry date. Single use.
Do not use concurrently with disinfectants containing quaternary ammonium salts, as hyaluronic acid may precipitate in their presence. Avoid the simultaneous administration of SYALOSET 2.000 with other products for intra-articular use, in order to prevent any possible interaction.

Storage
Store at a temperature not exceeding 25 °C in the original container and do not expose to light.
Do not freeze.
The expiry date refers to the product stored in its original packaging at a temperature not exceeding 25 °C.

Format
1 single-use pre-filled syringe of 30 mg/2 ml.