ANAURAN*EAR DROPS BTL 25ML

Anauran ear drops, solution
Polymyxin B sulfate, Neomycin sulfate, Lidocaine hydrochloride

What it is and what it is used for
Anauran contains the active ingredients polymyxin B sulfate, neomycin sulfate, and lidocaine hydrochloride.

The medicine is a combination of antibiotics and a local anesthetic.

Anauran is indicated in adults and children for the treatment of acute and chronic otitis.

Contact your doctor if you do not feel better or if you feel worse after three days.

What you need to know before taking the medicine
Do not use Anauran:
- if you are allergic (hypersensitive) to polymyxin B sulfate, neomycin sulfate, and lidocaine hydrochloride, or to any of the other ingredients of this medicine (listed in section 6)
- if you have a perforated eardrum, due to the risk of ear damage

Warnings and precautions
Contact your doctor or pharmacist before using Anauran.

The use of topical products such as Anauran, especially if prolonged, can lead to sensitization phenomena. In such cases, discontinue treatment and consult your doctor for appropriate therapy.
In the presence of deep or resistant infections, local medication should be supplemented with appropriate systemic antibiotic treatments.
As with other antibiotic medicines, prolonged treatments can lead to further infections (called “superinfections”) by germs that are resistant to the same antibiotic therapies.
Neomycin, one of the active ingredients in this medicine, can cause permanent hearing loss. The risk of ear damage is greater with prolonged use, therefore a treatment duration limited to 10 consecutive days is recommended.
If you have experienced allergic reactions or resistance with other antibiotics similar to neomycin (aminoglycosides), these may also occur with the use of Anauran.

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported following the administration of Anauran:

Frequency not known (frequency cannot be estimated from the available data)
• Allergic skin reaction (allergic dermatitis), itching
• Irritation at the application site
• Ear damage (ototoxicity)

Reporting of side effects
If you get any side effects, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects you can help provide more information on the safety of this medicine.