CLOZOL*VAGINAL CREAM 30G 2%

CLOZOL 2% vaginal cream
Clotrimazole

What it is and what it is used for
CLOZOL contains clotrimazole, an antifungal that inhibits the growth of fungi.

CLOZOL is used in adults and adolescents over 12 years of age for the treatment of localized symptoms resulting from vulvovaginal and glans (distal part of the penis) infections caused by previously diagnosed candida. These symptoms include itching, leukorrhea (whitish vaginal discharge), redness and swelling sensation of the vaginal mucosa and glans, burning when urinating.

Consult your doctor if you do not feel better or if you feel worse after 7 days of treatment.

What you need to know before taking the medicine
Do not use CLOZOL
- if you are allergic to clotrimazole or any of the other ingredients of this medicine (listed in section 6).

Warnings and precautions
Talk to your doctor or pharmacist before using CLOZOL if:
- you have suffered from the same disorders less than 2 months ago;
- you have fever, lower abdominal pain, back pain, foul-smelling vaginal discharge, nausea, vaginal bleeding and/or shoulder pain.

The use, especially if prolonged, of topical products (applied to the skin) can cause sensitization phenomena (acquisition of greater sensitivity); in this case, it is necessary to stop the treatment and consult your doctor or pharmacist.

Avoid contact with eyes. Do not ingest.

It is preferable to start and end the treatment in the intermenstrual period.

During the use of this medicine, avoid vaginal intercourse, because the infection could be transmitted to your partner.

Furthermore, in order to avoid re-infection, particularly in the presence of vulvitis or balanitis caused by Candida, local treatment of the partner is recommended.

Do not use tampons, vaginal douches, spermicides or other vaginal products during CLOZOL therapy.

During treatment with CLOZOL, the effectiveness and safety of latex products, such as condoms and diaphragms, may be reduced.

Children and adolescents
This medicine should not be used by children under 12 years of age.

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects may occur with the use of this medicine with unknown frequency (frequency cannot be estimated from the available data):

- anaphylactic reaction (severe allergic reaction);
- angioedema (swelling of the face, lips, mouth, tongue and throat that can cause problems with breathing and swallowing);
- hypersensitivity (allergy);
- syncope (fainting);
- hypotension (low blood pressure);
- dyspnea (difficulty breathing);
- abdominal pain;
- nausea;
- skin rash;
- urticaria (hives);
- exfoliation in the genital area;
- vaginal discharge;
- vaginal bleeding;
- discomfort in the genital area;
- erythema (redness) in the genital area;
- burning in the genital area;
- itching in the genital area;
- pain in the genital area;
- irritation, oedema (fluid accumulation) and pain at the application site.

Reporting of side effects
If you get any side effects, including any not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly via the national reporting system at: https://www.aifa.gov.it/content/segnalazionireazioni-avverse.
By reporting side effects you can help provide more information on the safety of this medicine.