Vaginal Gel

Description
Gel for the prevention and adjunctive treatment of lesions caused by human papillomavirus (HPV).
- Creates a defensive barrier that prevents the risk of HPV integration and the formation of new lesions.
- Adjuvant in the re-epithelialization of existing lesions.
- Stimulates the regeneration of the vaginal microbiota.
Papilocare is indicated for:
- controlling and helping to re-epithelialize the cervical transformation zone to prevent the risk of lesions (LSIL) caused by HPV;
- adjunctive treatment of intraepithelial lesions caused by HPV;
- repairing and helping to re-epithelialize cervico-vaginal mucosal lesions;
- treating cervico-vaginal mucosal dryness;
- rebalancing the vaginal microbiota;
- improving vaginal health;
- creating conditions for rapid healing of lesions caused by friction due to burning or itching;
- forming a protective film that rapidly reduces discomfort, creating suitable conditions to promote the natural healing process.
The main components of the formulation are:
- substances that allow the formation of a mucoadhesive gel on the cervico-vaginal mucosa, creating a protective film that enhances the barrier action of the product;
- hyaluronic acid niosomes, with tissue moisturizing action, which help maintain elasticity;
- beta-glucan niosomes: thanks to their antioxidant properties, they maintain the natural structure and function of the skin and mucous membranes;
- Centella asiatica phytosomes, with a reparative action on damaged mucous membranes;
- Coriolus versicolor extract, with re-epithelializing and repairing action on cervico-vaginal lesions and micro-lesions;
- neem extract, with emollient properties that promote the natural healing process;
- BioEcolia, a prebiotic that stimulates the growth of beneficial bacterial flora and rebalances the microbiota in the cervico-vaginal area;
- aloe vera extract with moisturizing, re-epithelializing, and repairing action on the cervico-vaginal area.
Papilocare is recommended for women (adults) who test positive for papillomavirus (HPV), regardless of the presence of lesions caused by the virus (ASCUS or LSIL).

How to use
The treatment duration is 6 months, with the possibility of extending the period further based on medical prescription. It is important to complete the entire course of treatment to achieve the expected results.
It is recommended to start treatment after the menstrual cycle.
First month: apply one cannula per day for 21 consecutive days, then suspend treatment for the next 7 days.
Subsequent months (from the second to the sixth): apply one cannula every other day for 21 days.
Suspending Papilocare treatment during the menstrual cycle is recommended only for the convenience of patients; there are no clinical incompatibilities.
Apply preferably before going to sleep.
It is compatible with condom use.
Discard any cannula that is open or broken. The cannula is designed to facilitate product administration. Insert the cannula into the vagina and apply pressure to release its contents. Then remove the cannula from the vagina while keeping it pressed so that it does not re-aspirate the dispensed product.
Some gel may remain inside the cannula; this does not mean that a dose lower than recommended has been dispensed, as the cannula releases a sufficient amount to cover the cervico-vaginal mucosa (3 ml). Discard the cannula after use. Do not reuse a used cannula or share it with other patients.

Warnings
Keep out of reach of children.
Consult your doctor if pregnant.
Do not use in case of known hypersensitivity to any of its components.
If discomfort is experienced after application, discontinue use of the product and consult a doctor.
There are no data available on the use of Papilocare with contraceptives (e.g., vaginal ring or female condom), so Papilocare is not recommended for women using these types of contraceptives. In case of pregnancy, consult your doctor before using Papilocare and use it under strict medical supervision.

Storage
Store at a temperature between 2°C and 25°C.
Shelf life when unopened: 42 months.

Format
Pack containing 21 cannulas of 5 ml.

Code 010/117