Description
Rigenoma Gauze Pads protect damaged skin while stimulating regeneration.
Ozoile in combination with hyaluronic acid, Aloe vera, Biting Stonecrop to optimize hydration and enhance tissue regeneration. Blackcurrant with cortisone-like action, glycyrrhetinic acid, Butcher's Broom, Calendula, to enhance anti-inflammatory action, alpha-lipoic acid with antioxidant damage prevention and repair action.
Releases immediately available O² which activates slowed mitochondrial metabolism, providing ready energy to cells. Reduces oxygen consumption linked to inflammation, infection, and degenerative processes. Reactivates microcirculation by stimulating the transcription of VEGF, a growth factor for angiogenesis.
Inactivates cyclo-lipo-oxygenases (COX₂) reducing prostaglandins responsible for pain and edema and activates aminooxidases (MAO and DAO) which degrade histamine and serotonin, the causes of redness and itching.
It has bactericidal-fungicidal-virustatic action: oxidation of the bacterial and fungal capsule-wall; inhibition of receptors on the viral surface; lengthening of recurrence times due to the stimulation of immune defenses.
Stimulates the synthesis of fibroblasts, collagen, and new vessels by acting on growth factors FGF, PDGF, EGF, VEGF, HIF-1-alpha. Promotes cell adhesion in the formation of new tissue by stimulating the transcription of e-cadherins.

Instructions for use
Apply one or more gauze pads depending on the size of the area to be treated, cover with sterile gauze or appropriate bandaging. Repeat the dressing twice a day or as directed by your doctor. The product can also be used in case of occlusive dressing.

Warnings
If you are being treated with hypoglycemic drugs, consult your doctor before using the product.

Storage
Shelf life for intact packaging: 48 months.

Format
Pack of 10 sachets.
Gauze pad size: 10x10 cm.

Code 0613

Bibliography
I. Zanardi, S. Burgassi, E. Paccagnini, M. Gentile, V. Bocci, and V. Travagli. What Is the Best Strategy for Enhancing the Eects of Topically Applied Ozonated Oils in Cutaneous Infections? Biomed Res Int. 2013 Oct 27.
Nathália R. de Almeida, Adilson Beatriz, Ana Camila Micheletti and Eduardo J. De Arruda, Ozonized vegetable oils and therapeutic properties: A review. Orbital, The Electronic Journal Of Chemistry, Volume 4, Number 4, October-December 2012.
Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM, Therapeutic eects of topical application of ozone on acute cutaneous wound healing. J Korean Med Sci, 12 June 2009.
N. Geweely. Antifungal Activity of ozonized olive oil. Int. J. Agri. Boil., Vol.8, No. 5, 2006 Koichi Tamoto, Akironi Yamazaki, Hiromi Nochi, Toshiaki Miura. Ozonides of olive oil methyl oleate inhibit the expression of cyclooxygenase -2 through the suppression of IkB/NFkB-dependent pathway in lipopolysaccharide-stimulated macrophage-like THP-1 cells. IOA17th World Ozone Congress- Strasbourg 2005.
L.A. Sechi, I. Lezcano, N. Nunez, M. Espim, I. Duprè, A. Pinna, P. Molicotti,G. Fadda and S. Zanetti. Antibacterial activity of ozonized sun ower oil. Journal of Applied Microbiology 2001, 90, 279±284.
Matsumoto, Akiyo; Shotaro Sakurai; Nariko Shinriki; Shigeru Suzuki & Toshiaki Miura, Therapeutic Eects of Ozonized Olive Oil in the Treatment of Intractable Fistula and Wound after Surgical Operation. Japan, J. Clin. Surg., 61(6) 7-13 (2000).